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What is Varicella-Zoster Antibody (IgG)? High and low values | Lab ...
A positive IgG result coupled with a positive IgM result suggests recent infection with varicella-zoster virus (VZV). This result should not be used alone to diagnose VZV infection and should be interpreted in the context of clinical presentation.
IgG Levels in Varicella-Zoster Virus Detection and Interpretation
Accurate interpretation of IgG antibody presence helps differentiate between past infections, recent exposure, and immunity status. This section will explore how these antibodies respond to VZV, diagnostic techniques used to measure them, and their clinical significance.
Varicella-Zoster Antibody, IgG Assay:Introduction, Test Result, Unit
The Varicella-Zoster IgG assay is typically performed using a blood sample. The results are reported as a numerical value, and the interpretation depends on the laboratory’s reference range.
Varicella-Zoster Antibody, IgG, Serum - Mayo Clinic Laboratories ...
The presence of detectable IgG-class antibodies indicates prior exposure to the varicella-zoster virus (VZV) through infection or immunization. Individuals testing positive are considered immune to varicella-zoster.
Varicella zoster Virus Antibody, IgG - MLabs
Single IgG levels are not useful for supporting the diagnosis of acute infection. Elevated levels in neonates should be followed up with studies to rule out the presence of maternal antibodies.
What is a normal Varicella-Zoster (VZV) IgG titer level?
The normal varicella zoster titer level can be determined by various methods, including radioimmunoassay and indirect immunofluorescence 2. A study found that the geometric mean titer of VZV-specific IgG was 1:6,309, and titers were greater than or equal to 1:16,384 in 20 subjects who had had varicella at least 20 years before testing 2.
Varicella-Zoster Antibody, IgG | Healthmatters.io
A positive IgG result coupled with a negative IgM result indicates previous vaccination to or infection with VZV. These individuals are considered to have protective immunity to reinfection.
Varicella Zoster IgG - National University Hospital-Singapore
A “reactive” result suggests previous exposure or immunisation to Varicella zoster.
Diagnostic Usefulness of Varicella Zoster Virus-Specific Immunoglobulin ...
For VZV IgG, we selected an optimal cut-off value of 844.5 mIU/mL (sensitivity 65.9% and specificity 75.0%) for acute-phase sera and 940.8 mIU/mL (sensitivity 83.6%, specificity 79.6%) for convalescent-phase sera to predict HZ.
Varicella-Zoster Virus Antibodies, IgG and IgM - ARUP Lab
IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. 0.90 ISR or less: Negative - No significant level of detectable varicella-zoster virus IgM antibody. 0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.